Can I take 5mg and Zopiclone together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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Taking diazepam and zopiclone together can cause extreme sleepiness, severe drowsiness, and a high risk of breathing difficulties. It can also lead to significant coordination problems, increasing the risk of falls and accidents.
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Why this happens
Both medications are 'central nervous system depressants'. They work in a similar way to slow down brain activity. When used together, their effects are added together (an additive effect), which can over-sedate the body.
What you should do
Back to contentsYou should not take these two medications together unless specifically instructed and closely monitored by your doctor. If you feel unusually sleepy, have shallow breathing, or feel very dizzy, seek medical help immediately. Do not drive or operate machinery if taking these medicines.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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