Can I take Adcal d3 and Alendronic acid together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking Adcal-D3 (calcium and vitamin D3) at the same time as alendronic acid can stop the alendronic acid from being absorbed into your body. This means the medicine for your bones will not work properly.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
Calcium binds to alendronic acid in the stomach, forming a large complex that the body cannot absorb into the bloodstream.
What you should do
Back to contentsYou must wait at least 30 minutes after taking your alendronic acid before taking your Adcal-D3 or any other food, drink, or medicine. Most doctors recommend taking alendronic acid first thing in the morning on an empty stomach, and then waiting at least 30 to 60 minutes before having breakfast or taking your calcium supplement.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Drug interactions checker
Can I take Lisinopril and Potassium together?
Taking lisinopril and potassium supplements together can cause the levels of potassium in your blood to become dangerously high (a condition called hyperkalaemia). While your body needs potassium for your heart and muscles to work, too much of it can lead to serious heart rhythm problems or even cause the heart to stop. Symptoms of high potassium can include muscle weakness, tingling sensations, or palpitations, but often there are no symptoms until the level is very high.

Drug interactions checker
Can I take Colecalciferol and Trazodone together?
There are no known significant interactions between colecalciferol (Vitamin D3) and trazodone. It is generally considered safe to take these two medications together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.