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Can I take Anoro ellipta inhalation powder and Metoprolol succ together?

Drug interaction guide

Metoprolol (a beta-blocker) and Anoro Ellipta (which contains vilanterol, a beta-agonist) work in opposite ways on the airways. Taking them together can make your inhaler less effective at opening your airways and may cause breathing difficulties or asthma-like symptoms. Additionally, metoprolol may lose some of its effectiveness in lowering blood pressure or controlling heart rate.

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Why this happens

Anoro Ellipta contains vilanterol, which stimulates 'beta-2' receptors to relax the muscles in the lungs. Metoprolol is a beta-blocker that blocks these same receptors. Because they compete for the same spots in the body, they effectively cancel each other out. Even though metoprolol is 'cardioselective' (targeting the heart), it can still affect the lungs, especially at higher doses.

You should consult your doctor before using these medicines together. Your doctor may prefer to switch you to a different type of blood pressure medication or monitor your lung function very closely. If you experience sudden wheezing, chest tightness, or difficulty breathing while taking both, seek medical advice immediately.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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