Can I take Ashwagandha and Vitamin B12 together?

Why this happens

Ashwagandha (Withania somnifera) and Vitamin B12 (cobalamin) use different pathways in the body. Ashwagandha is primarily metabolised by liver enzymes, while Vitamin B12 is absorbed in the small intestine and stored in the liver. They do not compete for absorption or interfere with each other's effects.

You can continue to take both supplements as directed. However, always inform your doctor or pharmacist about all supplements you are taking, especially if you have an underlying thyroid condition or are scheduled for surgery, as ashwagandha can affect thyroid hormone levels and may have a mild sedative effect.

Pregnancy

Do not use ashwagandha during pregnancy as it may have abortifacient effects (it could cause a miscarriage).

Autoimmune diseases (e.g., Lupus, Rheumatoid Arthritis, Multiple Sclerosis)

Ashwagandha can stimulate the immune system, which may worsen the symptoms of autoimmune conditions.

Hyperthyroidism (overactive thyroid)

Ashwagandha can increase thyroid hormone levels. You must avoid it if you have an overactive thyroid, as it may worsen your condition or interfere with thyroid medications.

Scheduled Surgery

Stop taking ashwagandha at least 2 weeks before surgery; it can slow down the central nervous system and may dangerously increase the effect of anaesthesia.

Alcohol

Ashwagandha has sedative properties and may enhance the effects of alcohol. Combining them can lead to excessive drowsiness, impaired coordination, and slowed reaction times. It is best to avoid or strictly limit alcohol while taking this supplement.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.