Can I take Ashwagandha and Vitamin C together?

Why this happens

Ashwagandha is an adaptogenic herb that works primarily on the body's stress response system (the adrenal glands), while vitamin C is a water-soluble antioxidant. They do not share the same metabolic pathways in the liver, nor do they interfere with each other's absorption or excretion.

You can safely take these two supplements together. It is usually best to take vitamin C with food to avoid stomach upset, and ashwagandha can be taken at any time of day, though many people prefer taking it in the evening. Always follow the dosage instructions on the product labels.

Pregnancy

Do not use ashwagandha during pregnancy as it may have abortifacient effects (it could cause a miscarriage).

Autoimmune diseases (e.g., Lupus, Rheumatoid Arthritis, Multiple Sclerosis)

Ashwagandha can stimulate the immune system, which may worsen the symptoms of autoimmune conditions.

Hyperthyroidism (overactive thyroid)

Ashwagandha can increase thyroid hormone levels. You must avoid it if you have an overactive thyroid, as it may worsen your condition or interfere with thyroid medications.

Surgery requiring general anaesthesia

Ashwagandha may slow down the central nervous system; you must stop taking it at least 2 weeks before a scheduled surgery to avoid dangerous interactions with anaesthetics.

Kidney stones or chronic kidney disease

High doses of Vitamin C can increase oxalate levels in urine, significantly raising the risk of developing kidney stones or causing kidney damage.

Alcohol

Ashwagandha has sedative properties. Combining it with alcohol can increase drowsiness, sleepiness, and impaired coordination. It is best to avoid or strictly limit alcohol while taking this supplement.

Caffeine (Coffee/Tea)

Large amounts of caffeine may slightly increase the amount of Vitamin C excreted in your urine, potentially reducing its effectiveness over time. Try to space out your caffeine intake and your supplement.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.