Can I take Atorvastatin and Mirabegron astellas together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking these two medicines together may slightly increase the level of atorvastatin in your blood. This could potentially increase the risk of side effects from the statin, such as muscle aches or pain.
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Why this happens
Mirabegron can slightly interfere with a protein (CYP3A4) and a transporter (P-gp) that the body uses to break down and remove atorvastatin. This means the atorvastatin stays in your system a bit longer than usual.
What you should do
Back to contentsYou can usually take these together, but you should be aware of any new or unusual muscle pain, tenderness, or weakness. If you notice these symptoms, or if you experience dark-coloured urine, contact your doctor. Your doctor may want to monitor you more closely when you first start taking them together or if your dose is increased.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Can I take Atorvastatin and Prednisolone together?
Taking atorvastatin and prednisolone together may increase the risk of muscle-related side effects, such as muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis, where muscle tissue breaks down and can cause kidney damage. Additionally, prednisolone can raise blood sugar levels, which may slightly reduce the effectiveness of atorvastatin in managing your cholesterol profile.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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