Can I take Azathioprine and Diltiazem together?
Drug interaction guide
Originally published 12 May 2026
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Taking diltiazem alongside azathioprine may increase the risk of side effects from azathioprine, particularly a drop in your white blood cell count. This can make you more likely to pick up infections. It may also increase the risk of anaemia (low red blood cells) or bruising.
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Why this happens
Diltiazem can slow down the liver's ability to process certain medications. This can lead to higher levels of azathioprine (and its active components) staying in your bloodstream for longer than intended.
What you should do
Back to contentsYou can usually take these medicines together, but your doctor should monitor you more closely. You will likely need more frequent blood tests to check your blood cell counts (FBC) and liver function. If you develop a fever, sore throat, unexplained bruising, or feel unusually tired, contact your doctor immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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