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Can I take Biotin and Isosorbide mononitrate together?

Drug interaction guide

There are no known direct interactions between biotin and isosorbide mononitrate. Biotin is a B-vitamin (B7) used for hair, skin, and nail health, while isosorbide mononitrate is a nitrate medication used to prevent chest pain (angina). They work in completely different ways in the body and do not interfere with each other's absorption or breakdown.

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Why this happens

Biotin is a water-soluble vitamin that acts as a coenzyme for carboxylase enzymes. Isosorbide mononitrate is a vasodilator that releases nitric oxide. These two substances do not share the same metabolic pathways (enzymes) in the liver, nor do they have opposing or additive effects on blood pressure or heart rate.

You can safely take biotin and isosorbide mononitrate together. However, you should always inform your doctor or pharmacist about all supplements you are taking. Note: High doses of biotin can interfere with certain laboratory blood tests (such as troponin tests used to diagnose heart attacks). If you need blood tests related to your heart condition, tell the medical staff you are taking biotin.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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