Can I take Biprosolol and Seroxat together?
Drug interaction guide
Originally published 12 May 2026
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Taking these two medicines together can cause your heart rate to slow down more than usual (bradycardia). It may also increase the levels of bisoprolol in your blood, which can lead to side effects like dizziness, feeling faint, or extreme tiredness.
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Why this happens
Seroxat (paroxetine) can block a specific enzyme in the liver (CYP2D6) that is responsible for breaking down bisoprolol. This causes bisoprolol to build up in your system. Additionally, both drugs can independently slow down the heart rate, leading to a combined effect.
What you should do
Back to contentsYou should speak to your doctor before taking these together. They may want to monitor your heart rate and blood pressure more closely, or they might adjust your dose of bisoprolol. If you feel very dizzy, faint, or notice a very slow pulse, seek medical advice.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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