Can I take Co-dydramol and Utrogestan together?
Drug interaction guide
Originally published 12 May 2026
Meets Patient’s editorial guidelines
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Both co-dydramol and Utrogestan (progesterone) can cause drowsiness, dizziness, and a feeling of being 'spaced out'. Taking them together may increase these effects, making you feel more tired or less alert than usual.
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Why this happens
Co-dydramol contains dihydrocodeine (an opioid) and Utrogestan is a hormone; both have a calming or sedative effect on the central nervous system. When taken together, these effects can add up.
What you should do
Back to contentsIt is generally safe to take these together, but you should be aware of how they affect you. Avoid driving, cycling, or using heavy machinery until you know how this combination makes you feel. If you feel excessively sleepy or have trouble breathing, contact your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
12 May 2026 | Originally published
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