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Can I take Furosemide and Pantaprozole together?

Drug interaction guide

Taking these two medicines together can lead to low levels of magnesium in your blood. This is more likely to happen if you take them together for a long time (usually more than three months). Low magnesium can cause symptoms like tiredness, muscle cramps, or an irregular heartbeat. In some cases, it can also lead to low levels of potassium or calcium.

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Why this happens

Both medicines can cause the body to lose magnesium. Furosemide (a water tablet) makes the kidneys flush out more magnesium in the urine. Pantoprazole (a stomach acid reducer) can interfere with how the gut absorbs magnesium from your food. When used together, these two effects combine.

You can take these medicines together, but your doctor may want to check your blood mineral levels (especially magnesium) with a simple blood test. If you experience unusual muscle twitches, spasms, or a racing heartbeat, contact your doctor. Do not stop taking your prescribed medication without speaking to a healthcare professional first.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 12 May 2026 | Originally published
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