Can I take Hydroxycarbamide and Hydroxychloroquine together?
Drug interaction guide
Originally published 25 Jan 2026
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Both hydroxycarbamide and hydroxychloroquine can lower your blood cell counts. Taking them together may increase the risk of developing serious infections, anaemia (low red blood cells), or bruising and bleeding problems. There is also a small risk that both medications could affect your heart rhythm or increase the risk of skin reactions.
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Why this happens
These drugs have 'additive' effects on the bone marrow. Hydroxycarbamide is designed to slow down the production of blood cells, and hydroxychloroquine can sometimes cause this as a side effect. When used together, the impact on your immune system and blood count is much stronger.
What you should do
Back to contentsYou must speak to your doctor before taking these two medicines together. If your doctor decides you need both, you will require very frequent blood tests to monitor your full blood count. Seek immediate medical help if you develop a fever, sore throat, unusual bruising, or extreme tiredness.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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