Can I take Hydroxycobalamin and Sukkarto together?
Drug interaction guide
Originally published 25 Jan 2026
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Sukkarto (metformin) can lower the levels of Vitamin B12 (hydroxocobalamin) in your body over time. However, taking hydroxocobalamin is actually the treatment for this effect, so they do not 'clash' in a harmful way.
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Why this happens
Sukkarto (metformin) can interfere with how the body absorbs Vitamin B12 from the gut. Hydroxocobalamin is a form of Vitamin B12 used to replace what is lost or missing.
What you should do
Back to contentsIt is safe and often necessary to take these together. If you are on long-term Sukkarto, your doctor may have prescribed hydroxocobalamin specifically to prevent a deficiency. Continue taking both as prescribed and have your B12 levels checked regularly by your GP.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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