Can I take Lactulose and Quinine together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between lactulose and quinine. However, if lactulose causes severe diarrhoea, it could lead to low potassium levels (hypokalaemia). Low potassium can increase the risk of serious heart rhythm problems when taking quinine.
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Why this happens
Lactulose is a laxative that can cause electrolyte imbalances (like low potassium) if used excessively. Quinine can affect the electrical activity of the heart (prolonging the QT interval). If potassium levels are low, this heart-related side effect of quinine is more likely to occur.
What you should do
Back to contentsIt is generally safe to take these together at recommended doses. However, if you develop severe or persistent diarrhoea while taking lactulose, stop using it and speak to your doctor, as this can affect your mineral levels and make quinine less safe for your heart.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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