Can I take Lansoprazole and Quetiapine together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking lansoprazole and quetiapine together is generally safe, but lansoprazole might slightly change how much quetiapine your body absorbs. This could potentially make the quetiapine slightly less effective for some people.
Additionally, both medications can occasionally cause drowsiness or dizziness, which might be more noticeable when taken together.
In this article:
You can usually take lansoprazole and quetiapine together, however quetiapine may cause drowsiness and dizziness, and both medicines can increase the risk of side effects in some people.
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Why this happens
Lansoprazole reduces stomach acid. Quetiapine needs a certain level of acidity to dissolve properly so the body can absorb it.
By making the stomach less acidic, lansoprazole may slightly lower the amount of quetiapine that gets into your bloodstream.
What you should do
Back to contentsYou can usually take these medicines together. However, you should monitor how you feel. If you notice your mood changing or your symptoms returning, or if you feel excessively sleepy or dizzy, speak to your doctor. It is often helpful to take these medications at the same time every day to keep levels steady.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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