Can I take Ashwagandha and Folic acid together?

Why this happens

Ashwagandha (Withania somnifera) and folic acid (Vitamin B9) are processed by different pathways in the body. Ashwagandha is primarily metabolised by liver enzymes, while folic acid is a water-soluble vitamin that does not interfere with those specific processes. They do not have overlapping effects that would cause a safety concern.

You can continue to take both supplements as directed. As with any supplement, it is best to stick to the recommended daily dose. If you are pregnant or have a specific medical condition like an overactive thyroid or an autoimmune disease, you should consult your GP before starting ashwagandha.

Pregnancy

Do not use ashwagandha if you are pregnant, as there is evidence it may cause miscarriage.

Surgery

Stop taking ashwagandha at least 2 weeks before scheduled surgery. It can slow down the central nervous system and may dangerously increase the effect of anaesthesia and other medications used during and after the procedure.

Vitamin B12 deficiency (Pernicious Anaemia)

Folic acid must not be taken alone if you have a Vitamin B12 deficiency. It can improve your blood count while allowing underlying nerve damage from the B12 deficiency to continue undetected, potentially leading to permanent neurological damage.

Alcohol

Ashwagandha may have sedative effects. Combining it with alcohol can increase drowsiness, sleepiness, and impaired coordination. It is best to avoid or strictly limit alcohol while taking this supplement.

Tea (Caffeine/Tannins)

Drinking large amounts of tea may interfere with the absorption of folic acid due to the presence of tannins and catechins. It is advisable to take your folic acid supplement at a different time of day than your tea.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.