Can I take Ashwagandha and Magnesium together?

Why this happens

Both ashwagandha and magnesium can influence GABA receptors in the brain, which are responsible for relaxation. While they work in different ways, their combined effect can be additive, meaning they may enhance each other's calming properties.

It is usually fine to take these together. However, if you find yourself feeling overly sleepy or lethargic, try taking them at different times of the day (for example, ashwagandha in the morning and magnesium before bed) or reduce the dose of one. Always consult your GP before starting new supplements if you are taking prescribed medication for anxiety or sleep.

Autoimmune diseases (e.g., lupus, rheumatoid arthritis, multiple sclerosis)

Ashwagandha can stimulate the immune system, which may worsen symptoms of autoimmune conditions or interfere with immunosuppressant medications

Thyroid disorders (Hyperthyroidism)

Ashwagandha may increase thyroid hormone levels; this can be dangerous for people with overactive thyroids or those taking thyroid hormone replacement therapy.

Severe Kidney Disease (Renal Impairment)

If your kidneys are not functioning properly, they cannot clear excess magnesium from the blood, leading to potentially life-threatening magnesium toxicity.

Alcohol

Ashwagandha has sedative properties. Combining it with alcohol can increase drowsiness, impair coordination, and significantly slow your reaction times. It is best to avoid or strictly limit alcohol while taking this supplement.

Large meals or high-fibre foods

Taking magnesium on an empty stomach can sometimes cause diarrhoea or stomach upset. However, very high-fibre meals may slightly reduce the absorption of magnesium. For most people, taking magnesium with a light meal is the best way to avoid stomach irritation.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.